Remember these?
About 13 years ago,
Thorazine®
brand of chlorpromazine
helped make them
obsolete.
Even more important, it helped to eliminate or modify delusions
and hallucinations, lessen confusion, and make the patient more
amenable to other forms of therapy.
In psychiatry, 'Thorazine' remains today's most widely prescribed ataractic.
Before prescribing, please see the complete prescribing information, including
side effects reported with phenothiazine derivatives and symptoms and
treatment of overdosage, in SK&F literature or PDR. The following is a brief
precautionary statement.
Contraindications: Comatose states or the presence of large amounts of C.N.S.
depressants. Precautions: Potentiation of C.N.S. depressants may occur
(reduce dosage of such agents when used concomitantly). Antiemetic effect
may mask signs of overdosage of toxic drugs or obscure diagnosis of other
conditions. Administer in pregnancy only when necessary for patient's welfare.
Possibility of drowsiness should be kept in mind for patients who drive
cars, etc. Side Effects: Drowsiness; dry mouth; nasal congestion; constipation;
amenorrhea; miosis; mild fever; weight gain; hypotensive effects, sometimes
severe with I.M. administration; epinephrine effects may be reversed;
dermatological reactions; parkinsonism-like symptoms on high dosages (in
rare instances, may persist); lactation and moderate breast engorgement (in
females on high dosages); and less frequently, cholestatic jaundice (use
cautiously in patients with liver disease). Side effects occurring rarely include:
mydriasis; agranulocytosis; skin pigmentation; lenticular and corneal deposits
(after prolonged substantial doses). Available: Tablets -- 10 mg., 25 mg.,
50 mg., 100 mg. and 200 mg. Ampuls -- 1cc. and 2cc. (25mg./cc).
Multiple-dose Vials -- 10 cc. (25mg./cc). Spansule® capsules -- 30 mg., 75 mg.,
150 mg., 200 mg. and 300 mg. Concentrate -- 30 mg./cc.
Additional information on 'Thorazine' is available on request.
Smith, Kline & French Laboratories, Philadelphia