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Marplan advertisement, 1960. Mental Hospitals, Vol. 11, No. 6. When "change of life" seems the end of life... With the advancing years, woman's vulnerability to depression often become intense. The future looms insecure; menopausal dysfunctions spark somatic concern. And as she faces losing a symbol of femininity, even suicidal panic may supervene. Menopausal depression has been lifted by Marplan -- even when withdrawal and loss of affect were severe. Episodes of depression can often be controlled by a brief schedule of Marplan treatment, ordinarily 10 mg t.i.d. In some patients, release of new psychic energies may be seen on Marplan in as little as three or four days. Extensive clinical trials have revealed no hepatitis attributable to Marplan. However, complete dosage information, available on request, should be consulted before administering Marplan. Supplied: 10-mg tablets in bottles of 100 and 1000. Consult literature and dosage instructions, available on request, before prescribing. MARPLAN® --1-benzyl-2-(5-methyl-3-isoxazolylcarbonyl)hydrazine ROCHE Laboratories Division of Hoffman-La Roche Inc. |