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Akineton advertisement, 1960 Mental Hospitals, Vol. 11, No. 7. DRUG-INDUCED PARKINSONISM IS ON THE RISE reflecting the growing use of potent tranquilizers. These extrapyramidal disturbances may be reduced by lowering tranquilizer dosage. * "It is almost always preferable, however, to merely add oral Akineton® ...since this avoids the risk of loss of therapeutic benefit and permits uninterrupted phenothiazine therapy." AKINETON® brand of biperiden a prompt, specific countermeasure to drug-induced akinesia motor restlessness ~ akathisia ~ torticollis ~ oculogyric crises ~ chorea remarkably safe -- "Akineton was not responsible for a single dangerous or toxic effect in the 500 patients treated."* Dosage: Doses required to achieve the therapeutic goal are variable and individually adjusted. The following are average doses. Drug-induced extrapyramidal disorders ~ 1 tablet (2 mg.) one to three times daily Parkinson's disease ~ 1 tablet (2 mg.) three or four timese daily Akineton hydrochloride tablets -- 2 mg., bisected, bottles of 100 and 1000. *Ayd, Frank J., Jr.: Drug-induced Extrapyramidal Reactions: Their Clinical Manifestations and Treatment with Akineton. Psychosomatics 1:143 (May-June) 1960. Knoll Pharmaceutical Company, Orange, New Jersey |