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Cogentin advertisement, 1974. Hospital & Community Psychiatry, Vol. 25, No. 5. patients most in need of phenothiazines are often least able to cope with their side effects COGENTIN® (Benztropine Mesylate ~ MSD) added to the regimen helps alleviate phenothiazine-induced extrapyramidal symptoms ~ In a recent study of 71 patients treated with antipsychotics, Cogentin, administered in a double-blind manner in various dosage schedules, was found to be highly successful in relieving phenothiazine-induced extrapyramidal symptoms.(1) Patients experienced relief of such symptoms as facial and hand tremors, muscle weakness, sensations of psychic and motor excitation, and akathisia. 1. Neu C, Dimascio A, Demirgian E: Antiparkinson medication in the treatment of extrapyramidal side effects: single or multiple daily doses? Curr Ther Res 14:246, May 1972. Contraindications: Children under three years of age; use cautiously in older children. For more detailed information, consult your MSD representative or see full prescribing information. Merck Sharp & Dohme, Division of Merck & Co., Inc. West Point, Pa. 19486 |